The Filbin lab gets spooky for Halloween! 🎃👻 Reviving a classic fairytale...
Welcome to Laurie Delatour!
We are excited to welcome Laurie Delatour MD PhD, a senior resident in the Boston Combined Residency Program in Pediatrics who will complete a research rotation in the lab for 3 months!
Costanza and Ernesto run the Chicago Marathon!
Costanza and Ernesto ran the Chicago Marathon with the Alex's Lemonade Stand Foundation to raise funds and awareness for childhood cancer research! Congratulations to both for this fantastic achievement!
Congratulations to Ilon Liu for winning the EANO Youngster Award!
Biggest congratulations to Filbin lab alumna Ilon for this amazing recognition at the European Society for Neuro-Oncology (EANO) annual meeting in Rotterdam!
Welcome to Lumeng!
The Filbin lab welcomes a new postdoctoral fellow, Lumeng (Jade) Jia! Lumeng completed her PhD at Peking University in China, where she developed methods to study chromatin 3D organization.
Lab Retreat in Woods Hole
The Filbin lab spent a beautiful sunny day together in Woods Hole - filled with laughter, memories and lots of good food!
Sara Danielli awarded the Postdoc Mobility Fellowship
Congratulations to Sara for being awarded the Postdoc Mobility Fellowship from the Swiss National Science Foundation!
Gustavo A.V. Cruzeiro awarded the DF/HCC T32 Training Grant in Cancer Neuroscience Congratulations to Gustavo for being selected as a trainee in this new NIH-funded T32 training program!
Matilde Pittarello presents at the Harvard-Armenise Foundation Annual Symposium
Congratulations to Matilde for delivering a fantastic presentation on her summer research project at Harvard Medical School. We are all so proud of you and will miss you so much!
Mid-Summer Lab BBQ!
We all gathered together to enjoy a delicious summer barbeque - Brazilian style!
Filbin lab turns 5!
We celebrated our 5abfulous birthday with cake! Congratulations to Mariella and all the lab members, past and present, for this important milestone!
Welcome to summer research interns Ernesto Luna Melendez and Matilde Pittarello!
Ernesto and Matilde are two incredibily talented medical students who are joining our lab for 2 months for their summer research internships. Ernesto is a rising second year medical student at Rush Medical College in Chicago and his internship is sponsored by the Kenneth F. Swaiman Medical Student Scholarship from the Child Neurology Foundation. Matilde is a fourth year medical student at Humanitas University in Milan, Italy, and her internship is sponsored by the Harvard-Armenise Foundation fellowship program. We are so excited to see the all amazing thing you will learn and accomplish in the lab!!
Pediatric SNO Conference in Washington D.C.
The entire Filbin lab attended the SNO 7th Bieannial Pediatric Neuro-Oncology Research Conference which was held in Washington D.C.! Mariella served as the conference scientific co-chair, and the Filbin lab was well-represented with 5 oral and 3 poster presentations! The conference was a success - we all returned feeling inspired and motivated to keep working hard at the bench to help children battling devastating brain tumors.
Welcome to Sophia Castellani!
Welcome to Sophia, who will be joining the lab as a research technician! Sophia recently graduated from Northeastern University with a degree in Psychology and Behavioral Neuroscience.
Welcome to Stephen Frederico!
Welcome to Stephen, a visiting medical student from the University of Pittsburgh! Stephen will spend two years in the lab and will pursue a Master's in Clinical Investigation from Harvard Medical School. Stephen is the recipient of the Medical Scholar Research Fellowship (MSRF) from the Physician-Scientist Support Foundation.
Welcome to Jacob Haase! Welcome to Jacob, who joins the lab as a postdoctoral fellow! Prior to joining the lab, Jacob studied the biology of thyroid cancers at Brigham and Women's Hospital in Boston.
Goodbye to Jacob Rozowsky After an amazing year working in the lab as a research techinican, Jacob will be leaving us to start his MD PhD degree at New York University Grossman School of Medicine! Best of luck, Jacob - we will miss you!!
Welcome to Costanza Lo Cascio! Welcome to Costanza, who joins our lab as a postdoctoral fellow! Costanza recently completed her PhD at the Barrow Neurological Insitute in Phoenix, Arizona, where she studied epigenetic dysregulation in adult brain tumors.
Joana attends the ChadTough Defeat DIPG Foundation Research Workshop As a fellow sponsored by the ChadTough Defeat DIPG Foundation, Joana was invited to attend the foundation's annual research workshop at the University of Michigan in Ann Harbor. All fellows were invited to participate in a day of plenary talks, presentations and workshops on immune therapy, cancer neuroscience, metabolism and clinical correlates.
Welcome to Sara Danielli! Welcome to Sara Danielli, who joins the lab as a postdoctoral fellow! Sara recently completed her PhD at the University Children's Hospital of Zurich in Switzerland, where she used single-cell transcriptomics to unravel the heterogeneity of alveolar rhabdomyosarcoma.
Lab Spring BBQ The lab came together on a chilly Sunday to organize a Brazilian-style BBQ to celebrate Easter, each other's company, and the arrival of the newest members of the Filbin lab, Sara and Costanza!
Goodbye to Jenna LaBelle After two productive years in the lab, our bioinformatic analyst Jenna will be moving on and starting a new exciting position at Tscan Therapeutics. We will miss her dearly and we wish her the very best as she embarks in her new role!
Dana-Farber/Harvard Cancer Center Cancer Neuroscience Retreat
The Filbin lab attended the inaugural Cancer Neuroscience Retreat organized by the Dana-Farber/Harvard Cancer Center and co-chaired by Dr. Mariella Filbin and Dr. Humsa Venkatesh. The retreat was packed with lots of fascinating science, clinical applications and engaging discussions within the larger Harvard cancer research community!
Lab Holiday Celebration The Filbin lab and alumni gathered together to celebrate the holiday season and the end of an incredibly successful year!
Happy holidays from the Filbin lab! ⛄️🎄
Paper Published in Nature Genetics 🚨 New Paper Alert! 🚨 Our work dissecting the single-cell transcriptomic, epigenomic and spatial architectures of H3-K27M diffuse midline gliomas is now published in Nature Genetics! Our work delineates how age and anatomical location shape glioma cell-intrinsic and -extrinsic features in light of the shared driver mutation. Congratulations to all authors and collaborators!
To read a News & Views commentary on our work by Dr. Li, please click here.
Joana awarded the ChadTough Defeat DIPG Postdoctoral Fellowship Congratulations to Joana, who was selected as the recipient of the 2023 ChadTough Fellowship Grant! With this 3-year fellowship, Joana will investigate therapeutic avenues to target the aberrant epigenome of diffuse midline gliomas.
Alicia awarded the Max Kade Fellowship Congratulations to Alicia, who was awarded a postdoctoral exchange research fellowship from the Max Kade Foundation!
2022 Society for Neuro-Oncology Annual Meeting and Education Day This year Mariella was one of the scientific chairs of the SNO Annual Meeting Education Day in Tampa Bay, Florida! Filbin lab alumna Ilon Liu was invited to give an oral presentation of her work on the spatiotemporal organization of diffuse midline gliomas.
Welcome to Katharina Bruckner!
The Filbin lab welcomes Katharina, a visiting PhD student from the Medical University of Vienna who will spend 2 months in the lab to learn new techniques and contribute to ongoing research projects!
Welcome to Alicia! The lab welcomes Alicia as a new postdoctoral fellow! Alicia is a resident in pediatric neuro-oncology at the Medical University of Vienna and will spend several years in the lab during her clinical training to complete a research fellowship.
Review Published in Neuro-Oncology 🚨 New Paper Alert! 🚨 In this review article published in Neuro-Oncology, we provide an overview of current single-cell techniques and discuss relevant biology and therapeutic insights uncovered by their application to primary brain tumors in children and adults.
Spooky Halloween! The Filbin lab dressed up as a UMAP plot! Scary RNA velocity - messy data, but we will figure it out!
Happy Halloween from the Filbin lab! 👻🎃
Welcome to Ella Perault! Welcome to Ella, a first-year student in the Harvard PhD Program in Neuroscience who will be completing a rotation in our lab! Prior to moving to Boston, Ella completed a post-bac at the Northwestern Feinberg School of Medicine, where she studied the mechanisms underlying chemoresistance in adult brain tumors.
Annual Filbin Lab BBQ We all gathered together on a chilly end-of summer day for our favorite annual tradition - the Filbin lab family BBQ! We had a great time eating lots of tasty food, plenty of laughter and amazing company.
Goodbye, Sebastian! After spending 6 months in the lab as a visting scientist, Sebastian Eder will return to the St. Anna's Children Cancer Research Institute in Vienna to complete his residency in Pediatrics. We will miss you and look forward for you to visit the lab again soon!
Filbin Lab Goes Gold for Childhood Cancer Awareness Month
In solidarity of Childhood Cancer Awareness month in September, the Filbin lab went gold to raise awareness and showcase our committment to ending pediatric brain tumors through creative and impactful research. 🎗️
Paper Published in Cancer Discovery
🚨 NewPaper Alert! 🚨 Our work describing how glioma stem cells in H3K27M-mutated tumors are dependent on core components of the mammalian BAF (SWI/SNF) chromatin remodeling complex is now published in Cancer Discovery! Congratualtions to all authors and collaborators!
To read a commentary on our work by Drs. Beytagh and Weiss, please click here.