Filbin Lab Philosophy

The Filbin Lab is focused on defining the plasticity and heterogeneity of pediatric brain tumors. By defining the programs that either control “stemness” or “differentiated” cancer cell states as well as the intrinsic and extrinsic factors influencing these states, we can develop novel approaches for new therapies.

Pediatric Brain Tumors: Current Active Research

• Diffuse Intrinsic Pontine Glioma (DIPG)
• Hemispheric High-grade Glioma and Gliomatosis Cerebri (GC-HGG)
• Ependymoma (EPN)
• Embryonal Tumor with Multilayered Rosettes (ETMR)

DIPG

GC-HGG

Ependymoma

ETMR